Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.37 |
| ▸ | DRD1 | P21728 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30695438 | 0.83 | CYP2D6 (0.50) | L3MBTL1CYP2D6CYP2C19HRH1CHRM2 | |
| SCHEMBL231127 | 0.82 | CYP2D6 (0.57) | L3MBTL1CYP2D6CYP2C19NOS3NOS1 | |
| SCHEMBL7118806 | 0.82 | L3MBTL1 (0.49) | L3MBTL1CYP2D6CYP2C19NOS3NOS1 | |
| Methane SCHEMBL28533749 | 0.80 | CYP2D6 (0.55) | L3MBTL1CYP2D6CYP2C19NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL6775520 | 0.80 | CYP2D6 (0.55) | L3MBTL1CYP2D6CYP2C19HRH1CHRM2 | |
| SCHEMBL25453080 | 0.80 | DHFR (0.46) | L3MBTL1CYP2D6CYP2C19KDM4EMAPK1 | |
| SCHEMBL5206210 | 0.80 | CYP2D6 (0.44) | L3MBTL1CYP2D6CYP2C19NOS3NOS1 | |
| SCHEMBL19828274 | 0.80 | HDAC6 (0.48) | L3MBTL1CYP2D6CYP2C19NOS3NOS2 | |
| SCHEMBL30639141 | 0.77 | ALDH1A1 (0.43) | L3MBTL1CYP2D6CYP2C19ADRA2AADRA2B | |
| SCHEMBL4904986 | 0.75 | CYP2D6 (0.50) | L3MBTL1CYP2D6CYP2C19HRH1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | US | disclosed |
| EP-1264820-A1 | NOVEL AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | H1-2, H1-0, H1-3 | L3MBTL1 1260/4885CYP2D6 3022/4885CYP2C19 2549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.