Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 9/20 | 0.65 |
| ▸ | MMP9 | P14780 | 9/20 | 0.65 |
| ▸ | MMP13 | P45452 | 9/20 | 0.65 |
| ▸ | MMP7 | P09237 | 8/20 | 0.65 |
| ▸ | MMP2 | P08253 | 8/20 | 0.65 |
| ▸ | MMP3 | P08254 | 7/20 | 0.65 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.59 |
| ▸ | MMP14 | P50281 | 2/20 | 0.59 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL405125 | 0.88 | MMP9 (0.66) | MMP1MMP9MMP13MMP7MMP2 | |
| SCHEMBL4915104 | 0.88 | MMP9 (0.66) | MMP1MMP9MMP13MMP7MMP2 | |
| SCHEMBL15228196 | 0.86 | MMP9 (0.59) | MMP1MMP9MMP13MMP7MMP2 | |
| SCHEMBL174865 | 0.86 | MMP9 (0.59) | MMP1MMP9MMP13MMP7MMP2 | |
| SCHEMBL255126 | 0.85 | MMP2 (0.67) | MMP1MMP9MMP13MMP7MMP2 | |
| SCHEMBL4916984 | 0.83 | MMP9 (0.60) | MMP1MMP9MMP13MMP7MMP2 | |
| SCHEMBL14025839 | 0.83 | MMP9 (0.60) | MMP1MMP9MMP13MMP7MMP2 | |
| SCHEMBL4431428 | 0.79 | MMP2 (1.00) | MMP1MMP9MMP13MMP7MMP2 | |
| SCHEMBL3618803 | 0.79 | MMP2 (1.00) | MMP1MMP9MMP13MMP7MMP2 | |
| SCHEMBL7082523 | 0.78 | MMP2 (1.00) | MMP1MMP9MMP13MMP7MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031298-A2 | ETHYNYLBENZENE DERIVATIVES | DUKE UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |