Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | NPC1 | O15118 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 1.00 |
| ▸ | JAK2 | O60674 | 1/20 | 1.00 |
| ▸ | FNIP1 | Q8TF40 | 1/20 | 0.58 |
| ▸ | FEM1B | Q9UK73 | 1/20 | 0.58 |
| ▸ | GPX4 | P36969 | 2/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23818004 | 1.00 | MAPT (1.00) | MAPTALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL25455689 | 0.90 | MAPT (0.82) | MAPTALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL23269360 | 0.82 | ALDH1A1 (0.70) | MAPTALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL15452398 | 0.81 | MAPT (0.67) | MAPTALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL20456266 | 0.80 | ALDH1A1 (0.66) | MAPTALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL23804991 | 0.74 | FNIP1 (1.00) | MAPTALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL21401891 | 0.74 | RAB9A (0.58) | MAPTALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL21392964 | 0.72 | NPC1 (0.62) | MAPTALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL31104078 | 0.72 | FNIP1 (0.58) | MAPTALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL23818010 | 0.72 | FNIP1 (0.58) | MAPTALDH1A1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230148299-A1 | FEM1B PROTEIN BINDING AGENTS AND USES THEREOF | FEM1B, GSKIP, FNIP1 | MAPT 2106/4885ALDH1A1 4563/4885NPC1 3656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.