Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2541161 | 0.93 | MMP8 (0.46) | MMP8L3MBTL1TDP1ALDH1A1GAA | |
| SCHEMBL10800745 | 0.82 | MMP8 (0.43) | MMP8L3MBTL1GAAPIN1SMN1; SMN2 | |
| SCHEMBL2761707 | 0.80 | MAPT (0.40) | MMP8L3MBTL1TDP1ALDH1A1GAA | |
| SCHEMBL20520440 | 0.75 | CES2 (0.40) | L3MBTL1ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL10679108 | 0.75 | MMP8 (0.50) | MMP8L3MBTL1TDP1GAAPIN1 | |
| SCHEMBL17999452 | 0.75 | CYP3A4 (0.44) | MMP8TDP1ALDH1A1MAPTMAPK1 | |
| SCHEMBL19996010 | 0.74 | MAPT (0.37) | L3MBTL1TDP1ALDH1A1GAAMAPT | |
| SCHEMBL7640821 | 0.74 | TDP1 (0.51) | MMP8TDP1PIN1SMN1; SMN2MEN1 | |
| SCHEMBL28978165 | 0.74 | ALDH1A1 (0.43) | TDP1ALDH1A1SMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL1904899 | 0.72 | MMP8 (0.56) | MMP8TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846944-B2 | Regeneration of 2,2′-cyclopropylidene-bis (oxazolines) | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2014-09-30 | — | — | US | disclosed |
| EP-2365967-B1 | REGENERATION OF 2,2`-CYCLOPROPYLIDENE-BIS(OXAZOLINES) | LATVIAN INST ORGANIC SYNTHESIS (LV) | 2013-01-09 | — | — | EP | disclosed |
| CN-102292325-A | Regeneration of 2, 2' -cyclopropylidene-bis (oxazolines) | — | 2011-12-21 | — | — | CN | disclosed |
| US-20110263864-A1 | REGENERATION OF 2,2'-CYCLOPROPYLIDENE-BIS (OXAZOLINES) | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263864-A1 | REGENERATION OF 2,2'-CYCLOPROPYLIDENE-BIS (OXAZOLINES) | PCNA, SRD5A2, LIG3 | MMP8 2172/4885L3MBTL1 4506/4885TDP1 3840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.