Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 7/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.45 |
| ▸ | PLAU | P00749 | 4/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 2/20 | 0.40 |
| ▸ | GRB2 | P62993 | 1/20 | 0.39 |
| ▸ | KLHL20 | Q9Y2M5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25455467 | 1.00 | KLKB1 (0.45) | KLKB1EPHA2PLAUCACNA1BCTSG | |
| SCHEMBL25455478 | 0.86 | KLKB1 (0.53) | KLKB1PLAUCACNA1BCTSG | |
| SCHEMBL25455242 | 0.84 | EPHA2 (0.45) | KLKB1EPHA2PLAUKLHL20 | |
| SCHEMBL25455440 | 0.83 | KLHL20 (0.54) | KLKB1PLAUKLHL20 | |
| SCHEMBL25456028 | 0.82 | KLKB1 (0.50) | KLKB1PLAUKLHL20 | |
| SCHEMBL25457484 | 0.82 | KLHL20 (0.51) | KLKB1PLAUKLHL20 | |
| SCHEMBL25455271 | 0.82 | PLAU (0.47) | KLKB1EPHA2PLAUKLHL20 | |
| SCHEMBL25455298 | 0.82 | KLHL20 (0.51) | KLKB1PLAUKLHL20 | |
| SCHEMBL25457616 | 0.81 | KLHL20 (0.53) | KLKB1PLAUCTSGKLHL20 | |
| SCHEMBL25455942 | 0.81 | PLAU (0.47) | KLKB1EPHA2PLAUKLHL20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230145835-A1 | Modulators of Alpha-4-beta-7 Integrin and MAdCAM | QUANTUM INTELLIGENCE CORP. (KR) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230145835-A1 | Modulators of Alpha-4-beta-7 Integrin and MAdCAM | ITGB7, ITGAM, ITGA4 | KLKB1 1100/4885EPHA2 579/4885PLAU 793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.