SCHEMBL25460141

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22161140	0.92	ALDH1A1 (0.41)	MAPTALDH1A1HPGDHSD17B10MEN1
	SCHEMBL22077546	0.91	ALDH1A1 (0.44)	MAPTALDH1A1HPGDHSD17B10MEN1
	SCHEMBL22138514	0.90	ALDH1A1 (0.43)	MAPTALDH1A1HPGDHSD17B10MEN1
	SCHEMBL23821289	0.90	ALOX5 (0.38)	ALOX5CHEK2MAPTALDH1A1HPGD
	SCHEMBL23845650	0.90	ALDH1A1 (0.38)	MAPTALDH1A1HPGDHSD17B10MEN1
	SCHEMBL25687045	0.90	ALOX5 (0.36)	ALOX5MAPTALDH1A1HPGDHSD17B10
	SCHEMBL23283925	0.89	ALDH1A1 (0.37)	CHEK2MAPTALDH1A1HPGDHSD17B10
	SCHEMBL22240791	0.89	ALDH1A1 (0.46)	ALOX5CHEK2MAPTALDH1A1HPGD
	SCHEMBL24215921	0.89	ALDH1A1 (0.46)	ALOX5CHEK2MAPTALDH1A1HPGD
	SCHEMBL22161063	0.89	ALDH1A1 (0.40)	ALOX5CHEK2MAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.