Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | DRD4 | P21917 | 5/20 | 0.48 |
| ▸ | DRD3 | P35462 | 5/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445564 | 0.81 | KDM4E (0.40) | DRD2DRD4DRD3WDR5L3MBTL1 | |
| SCHEMBL2414381 | 0.80 | DRD2 (0.55) | DRD2DRD4DRD3WDR5L3MBTL1 | |
| SCHEMBL4716398 | 0.79 | CA1 (0.58) | ACHEL3MBTL1TDP1NPC1MAPT | |
| SCHEMBL6249641 | 0.79 | NQO1 (0.74) | NQO1TDP1NPC1MAPT | |
| SCHEMBL6626845 | 0.78 | DRD2 (0.59) | DRD2DRD4DRD3L3MBTL1KCNH2 | |
| SCHEMBL313373 | 0.78 | DRD2 (0.64) | DRD2DRD4DRD3WDR5ACHE | |
| SCHEMBL1688857 | 0.78 | ACHE (0.52) | DRD2DRD4DRD3WDR5ACHE | |
| SCHEMBL11582957 | 0.77 | CA1 (0.55) | ACHETDP1MAPT | |
| SCHEMBL7432568 | 0.77 | DRD2 (0.57) | DRD2DRD4DRD3L3MBTL1KCNH2 | |
| Hydrochloric Acid SCHEMBL10552592 | 0.76 | DRD2 (0.50) | DRD2DRD4DRD3WDR5ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103880609-A | Method for preparing 3,4-dimethoxytoluene | USTC UNIV SCIENCE TECH CN | 2014-06-25 | — | — | CN | disclosed |
| US-20110263539-A1 | SHIP 1 MODULATOR COMPOUNDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-10-27 | — | — | US | disclosed |
| US-20100323990-A1 | SHIP 1 MODULATOR PRODRUGS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2010-12-23 | — | — | US | disclosed |
| EP-2035360-A1 | SHIP 1 MODULATOR COMPOUNDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2009-03-18 | — | — | EP | disclosed |
| EP-2035367-A1 | SHIP 1 MODULATOR PRODRUGS | The University of British Columbia (CA) | 2009-03-18 | — | — | EP | disclosed |
| US-20090047244-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS I | IDENIX PHARMACEUTICALS, INC. (US) | 2009-02-19 | — | — | US | disclosed |
| WO-2009014730-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2009-01-29 | — | — | WO | disclosed |
| WO-2007147252-A1 | SHIP 1 MODULATOR PRODRUGS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2007-12-27 | — | — | WO | disclosed |
| WO-2007147251-A1 | SHIP 1 MODULATOR COMPOUNDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2007-12-27 | — | — | WO | disclosed |
| US-3981886-A | Amino-benzimidazole derivatives | E. R. SQUIBB & SONS, INC. (US) | 1976-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323990-A1 | SHIP 1 MODULATOR PRODRUGS | PPM1D, PPM1G, PPM1F | DRD2 3073/4885DRD4 3615/4885DRD3 3422/4885 |
| US-20110263539-A1 | SHIP 1 MODULATOR COMPOUNDS | PPM1F, PPM1D, PPP1R1B | DRD2 4344/4885DRD4 4282/4885DRD3 4424/4885 |
| US-20090047244-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS I | SERPINB1, SPINT2, PRSS1 | DRD2 4809/4885DRD4 4772/4885DRD3 4745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.