Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CHRND | Q07001 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25463746 | 0.84 | KCNN4 (0.45) | AKR1C3AKR1C2HDAC3HDAC1HDAC2 | |
| SCHEMBL13448610 | 0.79 | MEN1 (0.49) | HDAC3HDAC1HDAC2HDAC6KCNN4 | |
| SCHEMBL1627216 | 0.79 | AKR1C3 (0.64) | AKR1C3AKR1C2HDAC3HDAC1HDAC2 | |
| SCHEMBL25464167 | 0.79 | NPC1 (0.43) | AKR1C3AKR1C2HDAC3HDAC1HDAC2 | |
| SCHEMBL25460809 | 0.79 | AKR1C3 (0.38) | AKR1C3AKR1C2HDAC3HDAC1HDAC2 | |
| SCHEMBL7472692 | 0.79 | CNR1 (0.51) | AKR1C3AKR1C2HDAC3HDAC1HDAC2 | |
| SCHEMBL25460782 | 0.77 | KCNN4 (0.50) | HDAC3HDAC1HDAC2HDAC6KCNN4 | |
| SCHEMBL13363407 | 0.76 | FFAR2 (0.50) | FFAR2NPC1RAB9AKDM4E | |
| SCHEMBL25460811 | 0.76 | SLC6A3 (0.40) | HDAC3KCNN4SLC6A3CES2CES1 | |
| SCHEMBL30443832 | 0.75 | TSHR (0.44) | HDAC3HDAC1HDAC2HDAC6LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | AKR1C3 3106/4885AKR1C2 2812/4885HDAC3 1173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.