Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25463175 | 0.93 | HTR5A (0.41) | HTR5ASIGMAR1MAPTGAAIDO1 | |
| SCHEMBL25463173 | 0.85 | HTR5A (0.42) | HTR5AMAPTGAAIDO1L3MBTL1 | |
| SCHEMBL25463179 | 0.82 | SIGMAR1 (0.40) | SIGMAR1MAPTGAAIDO1L3MBTL1 | |
| SCHEMBL20777511 | 0.75 | HTR5A (0.52) | HTR5ACDK5CDK5R1ADRA2AADRA2B | |
| SCHEMBL25463089 | 0.75 | SIGMAR1 (0.41) | SIGMAR1MAPTGAAIDO1L3MBTL1 | |
| SCHEMBL25463088 | 0.75 | HTR5A (0.42) | HTR5ASIGMAR1MAPTGAACYP19A1 | |
| SCHEMBL18173665 | 0.74 | NPC1 (0.50) | HTR5ASIGMAR1MAPTGAAIDO1 | |
| SCHEMBL25463176 | 0.73 | CHRNB2 (0.35) | SIGMAR1MAPTGAAIDO1L3MBTL1 | |
| SCHEMBL30763449 | 0.73 | NPC1 (0.48) | HTR5AMAPTGAASMN1; SMN2 | |
| SCHEMBL7015184 | 0.71 | MAPT (0.58) | SIGMAR1MAPTCYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081812-A2 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |