Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15156401 | 0.77 | ENPP2 (0.52) | ENPP2CA1CA2TTR | |
| SCHEMBL29825814 | 0.76 | TRPV4 (0.52) | ENPP2CYP11B1CYP11B2TRPV4 | |
| SCHEMBL211234 | 0.76 | TRPV4 (0.52) | ENPP2CYP11B1CYP11B2TRPV4 | |
| SCHEMBL29636030 | 0.75 | ENPP2 (0.39) | ENPP2CA1CA2MGLLTTR | |
| SCHEMBL13065321 | 0.75 | ENPP2 (0.39) | ENPP2CA1CA2MGLLTTR | |
| SCHEMBL18660330 | 0.75 | ENPP2 (0.39) | ENPP2 | |
| SCHEMBL16033846 | 0.73 | MAOB (0.43) | CYP11B1CYP11B2TRPV4AR | |
| SCHEMBL16321566 | 0.73 | TRPV4 (0.44) | CYP11B1CYP11B2TRPV4AR | |
| SCHEMBL22683618 | 0.73 | ENPP2 (0.48) | ENPP2CA1CA2TTR | |
| SCHEMBL29955038 | 0.73 | ENPP2 (0.48) | ENPP2CA1CA2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078369-A1 | BICYCLIC COMPOUND AND APPLICATION THEREOF | 贝达药业股份有限公司 | 2023-05-11 | — | — | WO | disclosed |