Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.34 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.34 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13065321 | 1.00 | ENPP2 (0.39) | ENPP2CA2CA1MGLLTTR | |
| SCHEMBL13065320 | 0.85 | CA1 (0.38) | ENPP2CA2CA1MGLLTTR | |
| SCHEMBL128893 | 0.77 | ENPP2 (0.46) | ENPP2CA2CA1MGLLTTR | |
| SCHEMBL25463182 | 0.75 | ENPP2 (0.42) | ENPP2CA2CA1MGLLTTR | |
| SCHEMBL28490899 | 0.75 | ENPP2 (0.44) | ENPP2CA2CA1MGLLTTR | |
| SCHEMBL22207451 | 0.73 | ENPP2 (0.42) | ENPP2CA2CA1MGLLTTR | |
| SCHEMBL29954381 | 0.73 | CA3 (0.52) | ENPP2CA2CA1MGLLTTR | |
| SCHEMBL309397 | 0.73 | CA3 (0.52) | ENPP2CA2CA1MGLLTTR | |
| SCHEMBL1158717 | 0.72 | ENPP2 (0.38) | ENPP2CA2CA1MGLLTTR | |
| SCHEMBL28736456 | 0.72 | ENPP2 (0.34) | ENPP2CA2CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024222767-A1 | CRYSTAL FORM OF BICYCLIC COMPOUND AND PREPARATION METHOD THEREFOR | 贝达药业股份有限公司 | 2024-10-31 | — | — | WO | disclosed |
| CN-113164458-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-114989164-B | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof | 詹森药业有限公司 | 2024-08-13 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-114989164-A | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof | 詹森药业有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-110062761-B | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof | 詹森药业有限公司 | 2022-05-13 | — | — | CN | disclosed |