Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27574154 | 0.87 | PLK1 (0.71) | PLK1LMNARAB9ATSHRNFKB1 | |
| SCHEMBL326978 | 0.86 | PLK1 (0.69) | PLK1LMNARAB9ATSHRNFKB1 | |
| SCHEMBL13415301 | 0.84 | L3MBTL1 (0.69) | PLK1LMNARAB9ATSHRNFKB1 | |
| SCHEMBL1021042 | 0.84 | PLK1 (0.67) | PLK1LMNARAB9ATSHRNFKB1 | |
| SCHEMBL6807698 | 0.84 | PLK1 (0.67) | PLK1LMNARAB9ATSHRNFKB1 | |
| SCHEMBL5843831 | 0.84 | PLK1 (0.67) | PLK1LMNARAB9ATSHRNFKB1 | |
| SCHEMBL8792955 | 0.83 | PLK1 (0.65) | PLK1LMNARAB9ATSHRNFKB1 | |
| SCHEMBL11962152 | 0.81 | PLK1 (1.00) | PLK1LMNARAB9ATSHRNFKB1 | |
| SCHEMBL13938063 | 0.81 | PLK1 (0.68) | PLK1LMNARAB9ATSHRNFKB1 | |
| SCHEMBL7554084 | 0.80 | PLK1 (0.97) | PLK1LMNARAB9ATSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183171-A1 | PREPARATION OF SUBSTITUTED 4-(N'-HYDROXYCARBAMIMIDOYL)BENZOIC ACIDS | BASF CHEMICALS INDIA PVT. LTD. (IN) | 2023-06-15 | — | — | US | disclosed |
| US-20230145982-A1 | PREPARATION OF SUBSTITUTED 3-ARYL-5-TRIFLUOROMETHYL-1,2,4-OXADIAZOLES | BASF SE (DE) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230145982-A1 | PREPARATION OF SUBSTITUTED 3-ARYL-5-TRIFLUOROMETHYL-1,2,4-OXADIAZOLES | CYP4F3, ACOX3, PEX3 | PLK1 3946/4885LMNA 2430/4885RAB9A 4076/4885 |
| US-20230183171-A1 | PREPARATION OF SUBSTITUTED 4-(N'-HYDROXYCARBAMIMIDOYL)BENZOIC ACIDS | PAH, HAAO, HNMT | PLK1 4531/4885LMNA 2011/4885RAB9A 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.