Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29246043 | 1.00 | CHRM2 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL83981 | 1.00 | CHRM2 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL720143 | 1.00 | CHRM2 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL60113 | 1.00 | CHRM2 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9093899 | 1.00 | CHRM2 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL31290858 | 1.00 | CHRM2 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Ammonia Solution, Strong SCHEMBL25381565 | 0.97 | CHRM2 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Water SCHEMBL9834733 | 0.97 | CHRM2 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Water SCHEMBL9674541 | 0.97 | CHRM2 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL27412184 | 0.97 | CHRM2 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12516039-B2 | N-linked isoquinoline amides as LRRK2 inhibitors, pharmaceutical compositions, and uses thereof | MERCK SHARP & DOHME LLC (US) | 2026-01-06 | — | — | US | claimed |
| US-12440479-B2 | Prevention or treatment of chronic organ injury | GEORG-AUGUST-UNIVERSITAET GOETTINGEN, STIFTUNG OEFFENTLICHEN RECHTS, UNIVERSITAETSMEDIZIN (DE) | 2025-10-14 | — | — | US | claimed |
| US-20250304577-A1 | TYK2 INHIBITORS | BIOGEN MA INC. | 2025-10-02 | — | — | US | claimed |
| EP-4399212-B1 | SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AG (DE) | 2025-07-02 | — | — | EP | claimed |
| CN-119654322-A | TYK2 inhibitors | 渤健马萨诸塞州股份有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119144034-A | High-strength PP material and application thereof in decorative film | 浙江锦盛装饰材料股份有限公司 | 2024-12-17 | — | — | CN | claimed |
| US-20240398784-A1 | C-LINKED ISOQUINOLINE AMIDES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2024-12-05 | — | — | US | claimed |
| US-20240381872-A1 | SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-11-21 | — | — | US | claimed |
| CN-118725636-A | Water-based free radical-cation mixed photo-curing ink and application thereof | 陈鑫 | 2024-10-01 | — | — | CN | claimed |
| EP-4408427-A1 | SYSTEM AND METHOD FOR STATIC AND DYNAMIC MRI SHIMMING | Merck Sharp & Dohme LLC (US) | 2024-08-07 | — | — | EP | claimed |
| US-4839384-A | ANALGESICS | E. R. SQUIBB & SONS, INC. (US) | 1989-06-13 | — | — | US | claimed |
| US-4820733-A | WITH PROSTACYCLIN OR PROSTACYCLIN MIMIC | E.R. SQUIBB & SONS, INC. (US) | 1989-04-11 | — | — | US | claimed |
| EP-0309801-A2 | Use of thromboxane A2 antagonists for the manufacture of a medicament for improving post-ischemic myocardial dysfunction | E.R. Squibb & Sons, Inc. (US) | 1989-04-05 | — | — | EP | claimed |
| US-4808627-A | Method of preventing or treating toxemia in pregnancy using a thromboxane A2 receptor antagonist | E. R. SQUIBB & SONS, INC. (US) | 1989-02-28 | — | — | US | claimed |
| US-4743697-A | Process for preparing 7-oxabicycloheptane amino-alcohol intermediates useful in making thromboxane A2 receptor antagonists and novel intermediates procuced therein | E. R. SQUIBB & SONS, INC. (US) | 1988-05-10 | — | — | US | claimed |
| US-4713453-A | TREATMENT OF BRAIN DISORDERS | Suntori Limited (JP) | 1987-12-15 | — | — | US | claimed |
| EP-0248435-A1 | Process for preparing 7-oxabicycloheptane amino-alcohol intermediates useful in making thromboxane A2 receptor antagonists and novel intermediates produced therein | E.R. Squibb & Sons, Inc. (US) | 1987-12-09 | — | — | EP | claimed |
| EP-0238883-A1 | Oxabicycloheptane derivatives, pharmaceutical composition and use | SUNTORY LIMITED (JP) | 1987-09-30 | — | — | EP | claimed |
| US-4687865-A | Process for preparing 7-oxabicycloheptane amino-alcohol intermediates useful in making thromboxane A2 receptor antagonists | E. R. SQUIBB & SONS, INC. (US) | 1987-08-18 | — | — | US | claimed |
| US-4515972-A | Intermediates and method for producing intermediates useful in the preparation of 7-oxabicycloheptane prostaglandin derivatives | E. R. SQUIBB & SONS, INC. (US) | 1985-05-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | TYK2, JAK2, JAK1 | CHRM2 3775/4885CHRM4 4522/4885CHRM5 4258/4885 |
| US-12440479-B2 | Prevention or treatment of chronic organ injury | FKBP2, DUSP3, FKBP1A | CHRM2 3948/4885CHRM4 4387/4885CHRM5 4698/4885 |
| US-20240381872-A1 | SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | DDT, TH, CBR3 | CHRM2 1566/4885CHRM4 2814/4885CHRM5 2649/4885 |
| US-20240398784-A1 | C-LINKED ISOQUINOLINE AMIDES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | LRRK2, CLK2, BRSK2 | CHRM2 2032/4885CHRM4 3935/4885CHRM5 3358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.