SCHEMBL25464109

SCHEMBL25464109

CC(C)(C(=O)NC1CC1)c1cccc(F)c1F

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ SSTR4 P31391 4/20 0.42
▸ EPHX2 P34913 3/20 0.41
▸ HPGD P15428 1/20 0.40
▸ TAS1R3 Q7RTX0 2/20 0.39
▸ TAS1R1 Q7RTX1 2/20 0.39
▸ TAS1R2 Q8TE23 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ SSTR1 P30872 1/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25464172 0.83 SSTR4 (0.44) L3MBTL1SSTR4HPGDTAS1R3TAS1R1
SCHEMBL25464188 0.82 KMT2A (0.47) SSTR4EPHX2HPGDSSTR1KMT2A
SCHEMBL25464178 0.81 EPHX2 (0.43) SSTR4EPHX2TAS1R3TAS1R1TAS1R2
SCHEMBL25460803 0.80 GAA (0.41) KDM4ERAB9AALDH1A1
SCHEMBL25464108 0.77 TAS1R3 (0.47) L3MBTL1SSTR4EPHX2HPGDTAS1R3
SCHEMBL1626654 0.74 CES2 (0.44) HPGD
SCHEMBL30501842 0.74 CES2 (0.44) HPGD
SCHEMBL25301048 0.73 PLCG1 (0.47) KDM4EKMT2ANPC1RAB9AALDH1A1
SCHEMBL3860550 0.73 KCNN4 (0.46) HPGDKMT2A
SCHEMBL26238626 0.72 HSD11B1 (0.45) SSTR4KMT2ARAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230151074-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-05-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230151074-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS GIPR, GLP1R, GCGR L3MBTL1 2173/4885SSTR4 82/4885EPHX2 3721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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