Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | PRMT3 | O60678 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.43 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.43 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25464496 | 0.85 | RAB9A (0.60) | RAB9ANPC1PRMT3ALDH1A1RECQL | |
| SCHEMBL25464452 | 0.83 | KMT2A (0.64) | SMN1; SMN2RAB9ANPC1PRMT3ALDH1A1 | |
| SCHEMBL25464505 | 0.82 | ALDH1A1 (0.60) | SMN1; SMN2RAB9ANPC1PRMT3ALDH1A1 | |
| SCHEMBL25464419 | 0.80 | EPHX1 (0.64) | RAB9ANPC1PRMT3ALDH1A1MEN1 | |
| SCHEMBL25464514 | 0.79 | NPC1 (0.60) | SMN1; SMN2RAB9ANPC1PRMT3ALDH1A1 | |
| SCHEMBL25464488 | 0.79 | EPHX2 (0.55) | RAB9ANPC1PRMT3ALDH1A1MEN1 | |
| SCHEMBL2751048 | 0.79 | RAB9A (0.97) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL23230964 | 0.79 | RAB9A (0.91) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL16223210 | 0.78 | NAMPT (0.58) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL25464480 | 0.78 | EPHX2 (0.62) | SMN1; SMN2PRMT3KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | SMN1; SMN2 1966/4885RAB9A 658/4885NPC1 2460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.