Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 6/20 | 0.65 |
| ▸ | CTSB | P07858 | 7/20 | 0.52 |
| ▸ | CTSK | P43235 | 7/20 | 0.52 |
| ▸ | CASP3 | P42574 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP4 | P49662 | 1/20 | 0.51 |
| ▸ | CASP5 | P51878 | 1/20 | 0.51 |
| ▸ | CASP9 | P55211 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.51 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30500174 | 1.00 | PSMB5 (0.65) | PSMB5CTSBCTSKCASP3CASP1 | |
| SCHEMBL16024932 | 1.00 | PSMB5 (0.65) | PSMB5CTSBCTSKCASP3CASP1 | |
| SCHEMBL12826819 | 1.00 | PSMB5 (0.65) | PSMB5CTSBCTSKCASP3CASP1 | |
| SCHEMBL6662946 | 0.87 | PSMB5 (0.55) | PSMB5CTSBCTSKCASP3CASP1 | |
| SCHEMBL23644903 | 0.85 | PSMB5 (0.63) | PSMB5CTSBCTSKCASP3CASP1 | |
| SCHEMBL6666188 | 0.84 | CTSB (0.57) | PSMB5CTSBCTSKCASP3CASP1 | |
| SCHEMBL22697479 | 0.83 | CASP3 (0.63) | PSMB5CTSBCTSKCASP3PSMB1 | |
| SCHEMBL29421135 | 0.83 | CASP3 (0.63) | PSMB5CTSBCTSKCASP3PSMB1 | |
| SCHEMBL30697417 | 0.83 | CASP3 (0.63) | PSMB5CTSBCTSKCASP3PSMB1 | |
| SCHEMBL24759756 | 0.83 | CTSK (0.61) | PSMB5CTSBCTSKPSMB1PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230148179-A1 | SMALL MOLECULE INHIBITORS OF SARS-CoV-2 VIRAL REPLICATION AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH | 2023-05-11 | — | — | US | disclosed |
| US-20230148179-A1 | SMALL MOLECULE INHIBITORS OF SARS-CoV-2 VIRAL REPLICATION AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230148179-A1 | SMALL MOLECULE INHIBITORS OF SARS-CoV-2 VIRAL REPLICATION AND USES THEREOF | ACE2, ACE, SARS1 | PSMB5 1104/4885CTSB 31/4885CTSK 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.