Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | CCR1 | P32246 | 3/20 | 0.53 |
| ▸ | CCR5 | P51681 | 3/20 | 0.53 |
| ▸ | CCR8 | P51685 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252978 | 0.89 | KDM4E (0.43) | KDM4ELMNACCR1CCR5CCR8 | |
| Bromide SCHEMBL28646418 | 0.88 | KDM4E (0.42) | KDM4ELMNACCR1CCR5CCR8 | |
| Phosphine SCHEMBL28440787 | 0.88 | KDM4E (0.42) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL12153028 | 0.82 | KDM4E (0.47) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL26965614 | 0.81 | DPP4 (0.41) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL31589455 | 0.81 | GABRA1 (0.44) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL1581213 | 0.79 | ALDH1A1 (0.44) | KDM4EL3MBTL1TDP1BLMALDH1A1 | |
| SCHEMBL16081691 | 0.78 | KDM4E (0.55) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL254265 | 0.76 | KDM4E (0.49) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL253731 | 0.76 | SLC2A1 (0.53) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180128767-A1 | Small Volume In Vitro Analyte Sensor | ABBOTT DIABETES CARE INC. (US) | 2018-05-10 | — | — | US | disclosed |
| US-9891185-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2018-02-13 | — | — | US | disclosed |
| US-9662057-B2 | Integrated sample acquisition and analyte measurement method | ABBOTT DIABETES CARE INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160334356-A1 | Small Volume In Vitro Analyte Sensor | THERASENSE, INC. | 2016-11-17 | — | — | US | disclosed |
| US-20160235350-A1 | Integrated Sample Acquisition and Analyte Measurement Device | THERASENSE, INC. | 2016-08-18 | — | — | US | disclosed |
| US-9341591-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-9316609-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-9291592-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2016-03-22 | — | — | US | disclosed |
| US-9271669-B2 | Method for integrated sample acquisition and analyte measurement device | ABBOTT DIABETES CARE INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-9234863-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-20040054267-A1 | Small volume in vitro analyte sensor | THERASENSE, INC. | 2004-03-18 | — | — | US | disclosed |
| US-20030199744-A1 | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator | THERASENSE, INC. (US) | 2003-10-23 | — | — | US | disclosed |
| US-6618934-B1 | Method of manufacturing small volume in vitro analyte sensor | THERASENSE, INC. | 2003-09-16 | — | — | US | disclosed |
| US-6592745-B1 | Analytical sensors for the detection of bioanalytes in a small volume sample; to monitor glucose in diabetic patients and lactate during critical care | THERASENSE, INC. | 2003-07-15 | — | — | US | disclosed |
| US-6591125-B1 | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator | THERASENSE, INC. | 2003-07-08 | — | — | US | disclosed |
| US-6461496-B1 | BLOOD GLUCOSE | THERASENSE, INC. | 2002-10-08 | — | — | US | disclosed |
| US-6338790-B1 | DETECTION OF BIOANALYTES IN A SMALL VOLUME SAMPLE; CONCENTRATION OF A BIOMOLECULE, SUCH AS GLUCOSE OR LACTATE, USING TECHNIQUES SUCH AS COULOMETRY, AMPEROMETRY, AND POTENTIOMETRY. AN ENZYME CAPABLE OF CATALYZING THE | THERASENSE, INC. | 2002-01-15 | — | — | US | disclosed |
| US-6299757-B1 | ANALYTICAL SENSORS FOR THE DETECTION OF BIOANALYTES; ESPECIALLY MONITORING GLUCOSE LEVELS IN DIABETIC PATIENTS | THERASENSE, INC. | 2001-10-09 | — | — | US | disclosed |
| EP-1119637-A1 | SMALL VOLUME $i(IN VITRO) ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR | Therasense, Inc. (US) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000020626-A1 | SMALL VOLUME IN VITRO ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR | THERASENSE, INC. (US) | 2000-04-13 | — | — | WO | disclosed |