SCHEMBL2546593

SCHEMBL2546593

CCCC(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)C(C(=O)OC1CC(C)(C)N(C)C(C)(C)C1)C(=O)OC1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.38
PKM P14618 1/20 0.38
HTT P42858 1/20 0.38
HMGCR P04035 2/20 0.38
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
ALDH1A1 P00352 7/20 0.34
KDM4E B2RXH2 4/20 0.34
MAPT P10636 4/20 0.34
TSHR P16473 3/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
THRB P10828 1/20 0.32
HPGD P15428 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
CACNA1A O00555 1/20 0.31
CACNA2D1 P54289 1/20 0.31
CACNB1 Q02641 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6875064 0.95 GAA (0.36) GAAPKMHTTHMGCRKMT2A
SCHEMBL25141789 0.86 HMGCR (0.39) GAAPKMHTTHMGCRKMT2A
SCHEMBL10000628 0.85 GAA (0.39) GAAPKMHTTHMGCRKMT2A
SCHEMBL13992714 0.85 GAA (0.35) GAAPKMHTTHMGCRKMT2A
SCHEMBL2687904 0.84 GAA (0.40) GAAPKMHTTHMGCRKMT2A
SCHEMBL12744431 0.81 GAA (0.36) GAAPKMHTTHMGCRKMT2A
SCHEMBL172351 0.81 GAA (0.35) GAAPKMHTTKMT2AMEN1
SCHEMBL23544539 0.81 GAA (0.35) GAAPKMHTTKMT2AMEN1
SCHEMBL334874 0.81 GAA (0.39) GAAPKMHTTHMGCRKMT2A
SCHEMBL7759198 0.80 GAA (0.37) GAAPKMHTTHMGCRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8753739-B2 UV-curing protective layer for thermoplastic substrates BAYER MATERIALSCIENCE AG (DE) 2014-06-17 US claimed
US-20070237967-A1 UV-curing protective layer for thermo-plastic substrates COVESTRO DEUTSCHLAND AG (DE) 2007-10-11 US claimed
US-11236209-B2 Methacrylic resin composition and shaped product ASAHI KASEI KABUSHIKI KAISHA (JP) 2022-02-01 US disclosed
US-20190256632-A1 METHACRYLIC RESIN COMPOSITION AND SHAPED PRODUCT ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-08-22 US disclosed
US-9957423-B2 Use of pressure-sensitive adhesive tapes for optical applications TESA SE (DE) 2018-05-01 US disclosed
US-20160200947-A1 Use of Pressure-Sensitive Adhesive Tapes for Optical Applications TESA SE (DE) 2016-07-14 US disclosed
US-8753739-B2 UV-curing protective layer for thermoplastic substrates BAYER MATERIALSCIENCE AG (DE) 2014-06-17 US disclosed
US-20110259390-A1 FILM FOR SEALING BACK SIDE OF SOLAR CELL, MATERIAL FOR SEALING BACK SIDE OF SOLAR CELL, AND A SOLAR CELL MODULE TORAY INDUSTRIES, INC. (JP) 2011-10-27 US disclosed
US-20070237967-A1 UV-curing protective layer for thermo-plastic substrates COVESTRO DEUTSCHLAND AG (DE) 2007-10-11 US disclosed
US-5369140-A Hydroxyphenyl triazines, clear topcoats CIBA-GEIGY CORPORATION (US) 1994-11-29 US disclosed