Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2E1 | P05181 | 3/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | AOC1 | P19801 | 3/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL827231 | 0.89 | TDP1 (0.40) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL10188339 | 0.84 | LMNA (0.41) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL6911269 | 0.78 | AOC1 (0.51) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL14485323 | 0.78 | RPS6KA3 (0.39) | RPS6KA3AOC1AOC3KDM4C | |
| SCHEMBL5106106 | 0.78 | RPS6KA3 (0.42) | CYP2A6RPS6KA3AOC1AOC3KDM4C | |
| SCHEMBL10954433 | 0.77 | CYP2E1 (0.51) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL9587755 | 0.76 | LMNA (0.40) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL20959793 | 0.76 | SLC6A2 (0.42) | CYP2D6CYP2A6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL18858524 | 0.74 | CYP2E1 (0.43) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL24426028 | 0.74 | CYP2E1 (0.43) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230148061-A1 | TEAD INHIBITORS AND USES THEREOF | THE EHE FOUNDATION | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230148061-A1 | TEAD INHIBITORS AND USES THEREOF | TEAD2, TEAD3, TEAD4 | CYP2E1 2101/4885CYP2C8 666/4885CYP2D6 1755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.