Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 7/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25109776 | 0.79 | HRH3 (0.46) | KDM4EMAPTALDH1A1PKMGAA | |
| SCHEMBL25110212 | 0.79 | KDM4E (0.42) | KDM4EMAPTALDH1A1PKMNCF1 | |
| SCHEMBL22790759 | 0.79 | KDM4E (0.42) | KDM4EMAPTALDH1A1PKMNCF1 | |
| SCHEMBL24513990 | 0.78 | KDM4E (0.41) | KDM4EMAPTALDH1A1PKMNCF1 | |
| SCHEMBL16812995 | 0.78 | CXCR4 (0.49) | KDM4EMAPTALDH1A1NCF1CXCR4 | |
| SCHEMBL22793930 | 0.78 | KDM4E (0.43) | KDM4EMAPTALDH1A1PKMGAA | |
| SCHEMBL22793929 | 0.77 | KDM4E (0.42) | KDM4EMAPTALDH1A1PKMGAA | |
| SCHEMBL24513989 | 0.76 | KDM4E (0.41) | KDM4EMAPTALDH1A1PKMNCF1 | |
| SCHEMBL17832850 | 0.75 | CXCR4 (0.49) | KDM4EMAPTALDH1A1NCF1CXCR4 | |
| SCHEMBL16812990 | 0.74 | CHRM2 (0.50) | KDM4EMAPTALDH1A1NCF1CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230149549-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230149549-A1 | SMARCA DEGRADERS AND USES THEREOF | SMARCA1, SMARCB1, SMARCE1 | KDM4E 613/4885MAPT 1203/4885ALDH1A1 3473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.