Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25469646 | 0.84 | CA2 (0.51) | — | |
| SCHEMBL25470068 | 0.84 | DNMT1 (0.42) | DNMT1 | |
| SCHEMBL25469566 | 0.84 | DNMT1 (0.42) | DNMT1 | |
| SCHEMBL25470067 | 0.82 | DNMT1 (0.43) | DNMT1 | |
| SCHEMBL10081644 | 0.80 | DNMT1 (0.49) | DNMT1 | |
| SCHEMBL12711700 | 0.80 | DNMT1 (0.45) | DNMT1 | |
| SCHEMBL2121896 | 0.80 | DNMT1 (0.38) | DNMT1 | |
| SCHEMBL10081721 | 0.80 | DNMT1 (0.38) | DNMT1 | |
| SCHEMBL2121900 | 0.80 | DNMT1 (0.38) | DNMT1 | |
| SCHEMBL2611589 | 0.80 | DNMT1 (0.41) | DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655502-B2 | Short pendant arm linkers for nucleotides in sequencing applications | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655502-B2 | Short pendant arm linkers for nucleotides in sequencing applications | POLRMT, POLM, POLN | DNMT1 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.