⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2581495 | 0.75 | TDP1 (0.39) | — | |
| SCHEMBL8540552 | 0.73 | LMNA (0.47) | — | |
| Hydrochloric Acid SCHEMBL9636444 | 0.72 | ALDH1A1 (0.38) | — | |
| SCHEMBL8213963 | 0.69 | CYP1A2 (0.62) | — | |
| SCHEMBL19953130 | 0.69 | LMNA (0.42) | — | |
| Hydrochloric Acid SCHEMBL8040631 | 0.69 | LMNA (0.42) | — | |
| SCHEMBL16215615 | 0.69 | — | — | |
| SCHEMBL61314 | 0.69 | — | — | |
| SCHEMBL61315 | 0.69 | — | — | |
| SCHEMBL12539192 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081841-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023081812-A2 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |