Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.50 |
| ▸ | CCR8 | P51685 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CCR5 | P51681 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83775 | 0.79 | PDE10A (0.48) | LMNAMAPTKDM4ECYP3A4PDE10A | |
| SCHEMBL28649569 | 0.78 | LMNA (0.53) | CCR1CCR8LMNACCR5TDP1 | |
| SCHEMBL10277172 | 0.77 | PDE10A (0.56) | CCR1CCR8LMNACCR5TDP1 | |
| Phenanthroline SCHEMBL31365745 | 0.75 | CCR1 (0.80) | CCR1CCR8LMNACCR5TDP1 | |
| SCHEMBL27940741 | 0.75 | PDE10A (0.54) | CCR1CCR8LMNACCR5TDP1 | |
| SCHEMBL10277537 | 0.74 | CCR1 (0.48) | CCR1CCR8LMNACCR5TDP1 | |
| Phenanthroline SCHEMBL9343811 | 0.73 | KDM4E (0.84) | CCR1CCR8LMNACCR5TDP1 | |
| Phenanthroline SCHEMBL27878295 | 0.71 | KDM4E (0.80) | CCR1CCR8LMNACCR5TDP1 | |
| SCHEMBL6930708 | 0.71 | MT-CO1 (0.45) | LMNAMAPTSMN1; SMN2KDM4EHTT | |
| Phenanthroline SCHEMBL29367277 | 0.71 | CCR1 (1.00) | CCR1CCR8LMNACCR5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334125-B2 | Nucleic acids encoding nitrilases | VERENIUM CORPORATION (US) | 2012-12-18 | — | — | US | disclosed |
| US-20110263839-A1 | Nucleic Acids Encoding Nitrilases | VERENIUM CORPORATION (US) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263839-A1 | Nucleic Acids Encoding Nitrilases | RNGTT, NSUN2, DNTT | CCR1 4816/4885CCR8 4494/4885LMNA 1303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.