Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19288538 | 1.00 | ALDH1A1 (0.39) | ALDH1A1L3MBTL3L3MBTL1NCF1TLR9 | |
| SCHEMBL806098 | 0.84 | — | — | |
| SCHEMBL26577467 | 0.82 | L3MBTL3 (0.44) | ALDH1A1L3MBTL3L3MBTL1NCF1GAA | |
| SCHEMBL14307143 | 0.82 | L3MBTL1 (0.44) | ALDH1A1L3MBTL3L3MBTL1NCF1GAA | |
| SCHEMBL23269640 | 0.82 | L3MBTL1 (0.44) | ALDH1A1L3MBTL3L3MBTL1NCF1GAA | |
| SCHEMBL26042916 | 0.82 | L3MBTL3 (0.47) | ALDH1A1L3MBTL3L3MBTL1NCF1GAA | |
| SCHEMBL17082653 | 0.82 | CYP2D6 (0.33) | L3MBTL3L3MBTL1 | |
| SCHEMBL20080153 | 0.81 | L3MBTL1 (0.34) | ALDH1A1L3MBTL3L3MBTL1NCF1KDM4E | |
| SCHEMBL3436969 | 0.79 | L3MBTL1 (0.46) | ALDH1A1L3MBTL3L3MBTL1NCF1GAA | |
| SCHEMBL12772837 | 0.79 | L3MBTL3 (0.46) | ALDH1A1L3MBTL3L3MBTL1NCF1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180432-A1 | COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-05-17 | — | — | EP | disclosed |