Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10289059 | 0.78 | CES2 (0.40) | MAPTTDP1ALDH1A1CES2 | |
| SCHEMBL17484882 | 0.76 | CES2 (0.39) | CES2 | |
| SCHEMBL2536484 | 0.74 | POLB (0.43) | POLBMAPTTDP1ALDH1A1NPSR1 | |
| SCHEMBL648441 | 0.74 | MAPT (0.39) | POLBMAPTTDP1ALDH1A1NPSR1 | |
| SCHEMBL23447111 | 0.72 | CES2 (0.43) | TDP1ALDH1A1CES2GAA | |
| SCHEMBL24305750 | 0.71 | POLB (0.41) | POLBMAPTTDP1ALDH1A1NPSR1 | |
| SCHEMBL12660072 | 0.70 | CES2 (0.41) | TDP1ALDH1A1CES2GAA | |
| SCHEMBL1148785 | 0.70 | MAPT (0.39) | POLBMAPTTDP1ALDH1A1NPSR1 | |
| SCHEMBL4977247 | 0.70 | MAPK1 (0.35) | POLBMAPTTDP1ALDH1A1NPSR1 | |
| SCHEMBL14213754 | 0.70 | ALDH1A1 (0.32) | TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083295-A1 | ESTER DERIVATIVES OF N4-HYDROXYCYTIDINE AND USE THEREOF | SUZHOU SPRING-SEA BIO-PHARMACEUTICALS CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |