SCHEMBL25474247

SCHEMBL25474247

CC(C)C[C@H](C(=O)C(C)(C)C)N(C)C(=O)[C@@H]1CCCN1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SCN4A P35499 1/20 0.39
GLI1 P08151 1/20 0.34
PRCP P42785 1/20 0.32
DPP7 Q9UHL4 2/20 0.32
TERT O14746 1/20 0.31
PFKFB2 O60825 1/20 0.30
PFKFB1 P16118 1/20 0.30
PFKFB3 Q16875 1/20 0.30
DPP4 P27487 2/20 0.30
FAP Q12884 1/20 0.30
DPP8 Q6V1X1 1/20 0.30
DPP9 Q86TI2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25551835 1.00 SCN4A (0.39) SCN4AGLI1PRCPDPP7TERT
SCHEMBL12214819 0.85 SCN4A (0.41) SCN4AGLI1PRCPDPP7TERT
SCHEMBL14508102 0.85 SCN4A (0.41) SCN4AGLI1PRCPDPP7TERT
SCHEMBL11663943 0.85 SCN4A (0.41) SCN4AGLI1PRCPDPP7
SCHEMBL14492967 0.84 SCN4A (0.40) SCN4AGLI1PRCPDPP7DPP4
SCHEMBL14492971 0.84 SCN4A (0.40) SCN4AGLI1PRCPDPP7DPP4
SCHEMBL12214823 0.83 SCN4A (0.39) SCN4AGLI1PRCPDPP7PFKFB2
SCHEMBL12214831 0.83 SCN4A (0.39) SCN4AGLI1PRCPDPP7PFKFB2
SCHEMBL11659883 0.82 SCN4A (0.39) SCN4AGLI1PRCPDPP7TERT
SCHEMBL11659292 0.81 SCN4A (0.38) SCN4AGLI1PRCPDPP7TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159594-A1 COMPOUNDS FOR USE IN VIRAL INFECTIONS PHARMA MAR, S.A. (ES) 2023-05-25 US disclosed
US-20230159594-A1 COMPOUNDS FOR USE IN VIRAL INFECTIONS PHARMA MAR, S.A. (ES) 2023-05-25 US disclosed
US-20230158102-A1 COMPOUNDS FOR USE IN THE TREATMENT OF CORONAVIRUS INFECTION PHARMA MAR, S.A. (ES) 2023-05-25 US disclosed
US-20230158102-A1 COMPOUNDS FOR USE IN THE TREATMENT OF CORONAVIRUS INFECTION PHARMA MAR, S.A. (ES) 2023-05-25 US disclosed
US-20230158104-A1 COMPOUNDS FOR USE IN AUTOIMMUNE CONDITIONS PHARMA MAR, S.A. (ES) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158102-A1 COMPOUNDS FOR USE IN THE TREATMENT OF CORONAVIRUS INFECTION ACE, SARS1, ACE2 SCN4A 1563/4885GLI1 4507/4885PRCP 55/4885
US-20230159594-A1 COMPOUNDS FOR USE IN VIRAL INFECTIONS OAT, MAVS, HAVCR2 SCN4A 2983/4885GLI1 4382/4885PRCP 1146/4885
US-20230158104-A1 COMPOUNDS FOR USE IN AUTOIMMUNE CONDITIONS SSB, HLA-DRB1, TPMT SCN4A 2938/4885GLI1 3385/4885PRCP 1713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.