Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL762770 | 0.92 | MAPT (0.68) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL742957 | 0.84 | PTGER4 (0.54) | MAPTALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7745470 | 0.83 | ALDH1A1 (0.66) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11314258 | 0.82 | PTGER4 (0.53) | MAPTALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL14839882 | 0.82 | KAT2B (0.64) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8718178 | 0.78 | MAPT (0.70) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6595723 | 0.77 | MAPT (0.65) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6198859 | 0.77 | KAT2B (0.80) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL869207 | 0.76 | KAT2B (0.55) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2729695 | 0.76 | ALDH1A1 (0.63) | MAPTALDH1A1RAB9ALMNAKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552208-A1 | IMIDAZOLYL-IMIDAZOLES AS KINASE INHIBITORS | Glaxo Group Limited (GB) | 2013-02-06 | — | — | EP | disclosed |
| US-20130018039-A1 | IMIDAZOLYL-IMIDAZOLES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2013-01-17 | — | — | US | disclosed |
| WO-2011123609-A1 | IMIDAZOLYL-IMIDAZOLES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2011-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018039-A1 | IMIDAZOLYL-IMIDAZOLES AS KINASE INHIBITORS | MAP3K19, MAP3K20, MAP3K3 | MAPT 2704/4885ALDH1A1 2664/4885RAB9A 1002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.