Drometrizole

Drometrizole

SCHEMBL6664698

Cc1ccc(O)c(-n2nc3ccccc3n2)c1.Oc1ccccc1

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.88
RAB9A P51151 8/20 0.88
LMNA P02545 1/20 0.88
ALDH1A1 P00352 5/20 0.52
SMN1; SMN2 Q16637 5/20 0.52
KDM4E B2RXH2 5/20 0.51
POLB P06746 2/20 0.48
MAPT P10636 5/20 0.47
HPGD P15428 4/20 0.47
TDP1 Q9NUW8 2/20 0.47
NPSR1 Q6W5P4 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 2/20 0.40
IGF2BP2 Q9Y6M1 1/20 0.40
THRB P10828 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Drometrizole SCHEMBL29350665 0.94 NPC1 (1.00) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL15616 0.94 NPC1 (1.00) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL2548258 0.94 NPC1 (1.00) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL27755727 0.94 NPC1 (1.00) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL7796640 0.89 NPC1 (0.90) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL3793068 0.88 NPC1 (0.88) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL890036 0.88 NPC1 (0.88) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL2728302 0.85 NPC1 (0.78) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL6667186 0.84 NPC1 (0.80) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
SCHEMBL3297579 0.83 NPC1 (0.81) NPC1RAB9ALMNAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1281790-B1 Volatile corrosion inhibitors and process for making them EXCOR KORROSIONSFORSCHUNG GMBH (DE) 2004-08-18 EP claimed
US-6752934-B2 USED IN PACKAGING OR IN STORAGE IN CLOSED SPACES FOR PROTECTION OF THE CONVENTIONAL METALS FOR USE SUCH AS IRON, CHROMIUM, NICKEL, TIN, ZINC, ALUMINUM, COPPER AND THEIR ALLOYS AGAINST ATMOSPHERIC CORROSION EXCOR KORROSIONSFORSCHUNG GMBH (DE) 2004-06-22 US claimed
WO-2003012170-A1 VAPOR-PHASE CORROSION-INHIBITORS AND METHOD FOR PREPARING THE SAME EXCOR KORROSIONSFORSCHUNG GMBH (DE) 2003-02-13 WO claimed
US-20030031583-A1 Vapor-phase corrosion inhibitors and method of preparing same EXCOR KORROSIONSFORSCHUNG GMBH (DE) 2003-02-13 US claimed
EP-1281790-A1 Volatile corrosion inhibitors and process for making them EXCOR Korrosionsforschung GmbH (DE) 2003-02-05 EP claimed