Drometrizole

Drometrizole

SCHEMBL890036

Cc1ccc(O)c(-n2nc3ccccc3n2)c1.OCCO

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.88
RAB9A P51151 8/20 0.88
LMNA P02545 1/20 0.88
KDM4E B2RXH2 4/20 0.55
ALDH1A1 P00352 5/20 0.52
SMN1; SMN2 Q16637 5/20 0.52
POLB P06746 2/20 0.50
MAPT P10636 5/20 0.47
HPGD P15428 4/20 0.47
TDP1 Q9NUW8 2/20 0.47
NPSR1 Q6W5P4 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
IGF2BP2 Q9Y6M1 1/20 0.40
THRB P10828 1/20 0.40
GAA P10253 2/20 0.39
GFER P55789 1/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Drometrizole SCHEMBL27755727 0.94 NPC1 (1.00) NPC1RAB9ALMNAKDM4EALDH1A1
Drometrizole SCHEMBL29350665 0.94 NPC1 (1.00) NPC1RAB9ALMNAKDM4EALDH1A1
Drometrizole SCHEMBL2548258 0.94 NPC1 (1.00) NPC1RAB9ALMNAKDM4EALDH1A1
Drometrizole SCHEMBL15616 0.94 NPC1 (1.00) NPC1RAB9ALMNAKDM4EALDH1A1
Drometrizole SCHEMBL6667186 0.90 NPC1 (0.80) NPC1RAB9ALMNAKDM4EALDH1A1
Drometrizole SCHEMBL7796640 0.89 NPC1 (0.90) NPC1RAB9ALMNAKDM4EALDH1A1
Drometrizole SCHEMBL3793068 0.88 NPC1 (0.88) NPC1RAB9ALMNAKDM4EALDH1A1
Drometrizole SCHEMBL6664698 0.88 NPC1 (0.88) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL3297579 0.83 NPC1 (0.81) NPC1RAB9ALMNAKDM4EALDH1A1
Drometrizole SCHEMBL15379 0.82 NPC1 (0.78) NPC1RAB9ALMNAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200307155-A1 DOUBLE-SIDED PRESSURE-SENSITIVE-ADHESIVE-LAYER-ATTACHED POLARIZING FILM, AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2020-10-01 US disclosed
US-10310333-B2 Double-sided pressure-sensitive-adhesive-layer-attached polarizing film, and image display device NITTO DENKO CORPORATION (JP) 2019-06-04 US disclosed
US-20180157125-A1 DOUBLE-SIDED PRESSURE-SENSITIVE-ADHESIVE-LAYER-ATTACHED POLARIZING FILM, AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2018-06-07 US disclosed
US-8530046-B2 Adhesive sheet for protecting coating film NITTO DENKO CORPORATION (JP) 2013-09-10 US disclosed
US-20130122688-A1 PRESSURE-SENSITIVE ADHESIVE SHEET FOR DICING AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE USING PRESSURE-SENSITIVE ADHESIVE SHEET FOR DICING NITTO DENKO CORPORATION (JP) 2013-05-16 US disclosed
EP-2502953-A1 LAMINATE FILM Nitto Denko Corporation (JP) 2012-09-26 EP disclosed
US-20110064946-A1 ADHESIVE SHEET FOR PROTECTING COATING FILM NITTO DENKO CORPORATION (JP) 2011-03-17 US disclosed
EP-2287265-A1 ADHESIVE SHEET FOR PROTECTING COATING FILM Nitto Denko Corporation (JP) 2011-02-23 EP disclosed
EP-2186849-A1 COMPOSITE FILM Nitto Denko Corporation (JP) 2010-05-19 EP disclosed