Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23713716 | 0.92 | OPRM1 (0.44) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL18200180 | 0.92 | OPRM1 (0.44) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL741919 | 0.90 | OPRM1 (0.42) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL9746299 | 0.90 | OPRM1 (0.42) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL16863783 | 0.89 | ADRB2 (0.41) | OPRM1LMNATSHRDNM1CYP3A4 | |
| SCHEMBL15297093 | 0.87 | OPRM1 (0.44) | OPRM1SPHK1LMNATSHRDNM1 | |
| SCHEMBL2621497 | 0.82 | KDM4E (0.50) | KDM4E | |
| SCHEMBL15628632 | 0.79 | — | — | |
| SCHEMBL10945950 | 0.79 | SMPD1 (0.48) | OPRM1SPHK1LMNATSHRTHRB | |
| SCHEMBL8526142 | 0.78 | TSHR (0.47) | OPRM1SPHK1LMNATSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081526-A1 | LIPID NANOPARTICLE COMPOSITIONS FOR DELIVERING CIRCULAR POLYNUCLEOTIDES | ORNA THERAPEUTICS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |