Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746299 | 1.00 | OPRM1 (0.42) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL15297093 | 0.98 | OPRM1 (0.44) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL15297095 | 0.90 | — | — | |
| SCHEMBL25484377 | 0.90 | OPRM1 (0.46) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL15628632 | 0.90 | — | — | |
| SCHEMBL23713716 | 0.83 | OPRM1 (0.44) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL18200180 | 0.83 | OPRM1 (0.44) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL2848647 | 0.80 | LMNA (0.42) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL1068793 | 0.80 | LMNA (0.42) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL10958705 | 0.80 | LMNA (0.42) | OPRM1SPHK1LMNADNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430134-B1 | METHOD USING IMIDES AND BIS-AMIDES AS FRICTION MODIFIERS IN LUBRICANTS | LUBRIZOL CORP (US) | 2016-03-16 | — | — | EP | disclosed |
| US-9006156-B2 | Imides and bis-imides as friction modifiers in lubricants | THE LUBRIZOL CORPORATION (US) | 2015-04-14 | — | — | US | disclosed |
| US-8455410-B2 | Lubricating oil composition | INFINEUM INTERNATIONAL LIMITED (GB) | 2013-06-04 | — | — | US | disclosed |
| US-20120122744-A1 | Imides and Bis-Imides as Friction Modifiers in Lubricants | THE LUBRIZOL CORPORATION (US) | 2012-05-17 | — | — | US | disclosed |
| EP-2453000-A1 | Lubricating Oil Composition comprising a hydrogenated imide derived from a Diels-Alder adduct of maleic anhydride and a furan | Infineum International Limited (GB) | 2012-05-16 | — | — | EP | disclosed |
| US-20120111299-A1 | LUBRICATING OIL COMPOSITION | INFINEUM INTERNATIONAL LIMITED (GB) | 2012-05-10 | — | — | US | disclosed |
| EP-2430134-A1 | IMIDES AND BIS-AMIDES AS FRICTION MODIFIERS IN LUBRICANTS | The Lubrizol Corporation (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132318-A1 | IMIDES AND BIS-AMIDES AS FRICTION MODIFIERS IN LUBRICANTS | THE LUBRIZOL CORPORATION (US) | 2010-11-18 | — | — | WO | disclosed |