Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 4/20 | 0.37 |
| ▸ | PIM1 | P11309 | 9/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 9/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25484466 | 0.85 | LIMK1 (0.45) | LIMK1PIM1PIM2PIM3 | |
| SCHEMBL25485629 | 0.82 | PIM1 (0.39) | ALOX5LIMK1PIM1PIM2PIM3 | |
| SCHEMBL25485006 | 0.80 | LIMK1 (0.35) | LIMK1PIM1PIM2PIM3 | |
| SCHEMBL25484460 | 0.78 | PIM1 (0.35) | LIMK1PIM1PIM2PIM3 | |
| SCHEMBL25490264 | 0.77 | LIMK1 (0.40) | LIMK1PIM1PIM2 | |
| SCHEMBL25484784 | 0.77 | ALOX5 (0.37) | ALOX5PIM1PIM2PIM3PRKDC | |
| SCHEMBL25484880 | 0.77 | LIMK1 (0.35) | LIMK1PIM1PIM2PIM3 | |
| SCHEMBL21691666 | 0.74 | ALOX5 (0.51) | ALOX5LIMK1PIM1PRKDCSQOR | |
| SCHEMBL19887649 | 0.72 | ALOX5 (0.42) | ALOX5LIMK1PIM1PIM2PIM3 | |
| SCHEMBL29993235 | 0.72 | ALOX5 (0.55) | ALOX5LIMK1PIM1PIM2PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078812-A1 | BENZOFURO[3,2-D]PYRIMIDINO-2,4-DICARBONITRIL DERIVATIVES AND SIMILAR COMPOUNDS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2023-05-11 | — | — | WO | disclosed |