Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TNKS | O95271 | 2/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25485629 | 0.86 | PIM1 (0.39) | LIMK1EGLN1MAPTTNKSTNKS2 | |
| SCHEMBL25490263 | 0.83 | MAPT (0.42) | LIMK1CDK5CDK5R1HRH4MEN1 | |
| SCHEMBL17030414 | 0.83 | MAPT (0.48) | LIMK1CDK5CDK5R1HRH4MEN1 | |
| SCHEMBL25484466 | 0.79 | LIMK1 (0.45) | LIMK1PIM1PIM2 | |
| SCHEMBL25484787 | 0.77 | ALOX5 (0.41) | LIMK1PIM1PIM2 | |
| SCHEMBL25490266 | 0.75 | EGLN1 (0.41) | MEN1KMT2ANPSR1KDM4ETSHR | |
| SCHEMBL25484460 | 0.74 | PIM1 (0.35) | LIMK1PIM1PIM2 | |
| SCHEMBL1512630 | 0.73 | GPR3 (0.40) | LIMK1CDK5CDK5R1MEN1KMT2A | |
| SCHEMBL14629295 | 0.73 | GPR3 (0.41) | LIMK1CDK5CDK5R1KDM4EEGLN1 | |
| SCHEMBL25484880 | 0.71 | LIMK1 (0.35) | LIMK1EGLN1PIM1PIM2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078812-A1 | BENZOFURO[3,2-D]PYRIMIDINO-2,4-DICARBONITRIL DERIVATIVES AND SIMILAR COMPOUNDS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2023-05-11 | — | — | WO | disclosed |