Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 11/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 10/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 2/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25484466 | 0.87 | LIMK1 (0.45) | PIM1PIM2PIM3LIMK1 | |
| SCHEMBL25490264 | 0.86 | LIMK1 (0.40) | PIM1PIM2LIMK1MAPTGPR3 | |
| SCHEMBL25484787 | 0.82 | ALOX5 (0.41) | PIM1PIM2PIM3LIMK1ALOX5 | |
| SCHEMBL25485006 | 0.81 | LIMK1 (0.35) | PIM1PIM2PIM3LIMK1 | |
| SCHEMBL25484460 | 0.81 | PIM1 (0.35) | PIM1PIM2PIM3LIMK1 | |
| SCHEMBL25490606 | 0.78 | ADORA2A (0.34) | MAPT | |
| SCHEMBL25484880 | 0.74 | LIMK1 (0.35) | PIM1PIM2PIM3LIMK1EGLN1 | |
| SCHEMBL20030284 | 0.72 | LIMK1 (0.41) | PIM1PIM2PIM3LIMK1MAPT | |
| SCHEMBL15836057 | 0.72 | GPR3 (0.67) | PIM3LIMK1MAPTPTGIRGPR3 | |
| SCHEMBL20706794 | 0.72 | GPR3 (0.67) | PIM3LIMK1MAPTPTGIRGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078812-A1 | BENZOFURO[3,2-D]PYRIMIDINO-2,4-DICARBONITRIL DERIVATIVES AND SIMILAR COMPOUNDS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2023-05-11 | — | — | WO | disclosed |