Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 3/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 3/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.35 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20465424 | 0.87 | FOLH1 (0.43) | FOLH1NOD1SLC7A5MMEERAP2 | |
| SCHEMBL18452391 | 0.87 | FOLH1 (0.43) | FOLH1NOD1SLC7A5MMEERAP2 | |
| SCHEMBL20468541 | 0.85 | ANPEP (0.32) | FOLH1MMEERAP2ANPEPRNPEP | |
| SCHEMBL20468520 | 0.85 | L3MBTL1 (0.39) | NOD1MMEERAP2ANPEPRNPEP | |
| SCHEMBL20468544 | 0.85 | FOLH1 (0.46) | FOLH1NOD1SLC7A5MMEERAP2 | |
| SCHEMBL25760735 | 0.83 | FOLH1 (0.46) | FOLH1NOD1SLC7A5MMEERAP2 | |
| SCHEMBL25488443 | 0.83 | NPY4R (0.35) | MMEERAP2ANPEPRNPEPDNPEP | |
| SCHEMBL25760775 | 0.83 | L3MBTL1 (0.37) | NOD1 | |
| SCHEMBL18452768 | 0.81 | FOLH1 (0.38) | FOLH1NOD1SLC7A5MMEERAP2 | |
| SCHEMBL14941316 | 0.81 | FOLH1 (0.64) | FOLH1NOD1SLC7A5MMENAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328827-B1 | PRODRUGS OF GLUTAMINE ANALOGS | UNIV JOHNS HOPKINS (US) | 2023-07-05 | — | — | EP | disclosed |
| WO-2023081832-A1 | METHODS FOR PREVENTING AND TREATING ACUTE KIDNEY INJURY | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-05-11 | — | — | WO | disclosed |