Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.36 |
| ▸ | PPID | Q08752 | 1/20 | 0.34 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 2/20 | 0.32 |
| ▸ | METAP1 | P53582 | 2/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | CAD | P27708 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25760775 | 0.97 | L3MBTL1 (0.37) | L3MBTL1KMT2APOLBNOD1PPID | |
| SCHEMBL20468541 | 0.88 | ANPEP (0.32) | ANPEPRNPEPMMEDNPEPERAP2 | |
| SCHEMBL29465612 | 0.88 | L3MBTL1 (0.39) | L3MBTL1KMT2APOLBNOD1PPID | |
| SCHEMBL18452348 | 0.88 | L3MBTL1 (0.39) | L3MBTL1KMT2APOLBNOD1PPID | |
| SCHEMBL20465429 | 0.88 | L3MBTL1 (0.39) | L3MBTL1KMT2APOLBNOD1PPID | |
| SCHEMBL20468542 | 0.88 | L3MBTL1 (0.43) | L3MBTL1KMT2APOLBNOD1METAP2 | |
| SCHEMBL25760765 | 0.87 | L3MBTL1 (0.42) | L3MBTL1KMT2APOLBNOD1PPID | |
| SCHEMBL25487396 | 0.85 | FOLH1 (0.43) | NOD1ANPEPRNPEPMMEDNPEP | |
| SCHEMBL20465440 | 0.85 | CTSL (0.39) | L3MBTL1KMT2APOLBNOD1PPID | |
| SCHEMBL18452352 | 0.85 | CTSL (0.39) | L3MBTL1KMT2APOLBNOD1PPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328827-B1 | PRODRUGS OF GLUTAMINE ANALOGS | UNIV JOHNS HOPKINS (US) | 2023-07-05 | — | — | EP | disclosed |
| WO-2023081832-A1 | METHODS FOR PREVENTING AND TREATING ACUTE KIDNEY INJURY | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-05-11 | — | — | WO | disclosed |
| US-20180222930-A1 | PRODRUGS OF GLUTAMINE ANALOGS | DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C), AS COLLATERAL AGENT | 2018-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180222930-A1 | PRODRUGS OF GLUTAMINE ANALOGS | GLUL, GLS, GLS2 | L3MBTL1 406/4885KMT2A 2112/4885POLB 2076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.