Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 9/20 | 0.35 |
| ▸ | NPY1R | P25929 | 6/20 | 0.35 |
| ▸ | NPY2R | P49146 | 4/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.33 |
| ▸ | IL1RN | P18510 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 2/20 | 0.30 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.30 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20468541 | 0.97 | ANPEP (0.32) | NPY4RNPY1RBIRC2ERAP2MME | |
| SCHEMBL20465433 | 0.89 | CTSB (0.37) | NPY4RNPY1RNPY2RNPY5RBIRC2 | |
| SCHEMBL25760775 | 0.89 | L3MBTL1 (0.37) | NPY4RNPY1RNPY2RNPY5RBIRC2 | |
| SCHEMBL20468520 | 0.85 | L3MBTL1 (0.39) | ERAP2MMEANPEPRNPEPDNPEP | |
| SCHEMBL20465427 | 0.85 | CTSL (0.32) | BIRC2ERAP2ANPEPRNPEPDNPEP | |
| SCHEMBL18451208 | 0.85 | CTSL (0.32) | BIRC2ERAP2ANPEPRNPEPDNPEP | |
| SCHEMBL18476683 | 0.84 | MME (0.34) | NPY4RNPY1RBIRC2ERAP2MME | |
| SCHEMBL26946628 | 0.84 | MME (0.34) | NPY4RNPY1RBIRC2ERAP2MME | |
| SCHEMBL21473358 | 0.83 | BIRC2 (0.33) | NPY4RNPY1RNPY2RBIRC2IL1RN | |
| SCHEMBL25487396 | 0.83 | FOLH1 (0.43) | ERAP2MMEANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081832-A1 | METHODS FOR PREVENTING AND TREATING ACUTE KIDNEY INJURY | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-05-11 | — | — | WO | disclosed |