Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VPS4B | O75351 | 1/20 | 0.57 |
| ▸ | VCP | P55072 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24837125 | 0.73 | VPS4B (1.00) | VPS4BVCPSLC6A4 | |
| Bromide SCHEMBL11583932 | 0.67 | SCN5A (0.55) | VPS4BVCPNPSR1CNR1MITF | |
| SCHEMBL29387074 | 0.66 | ACHE (0.67) | LMNAMAPK1HTTMPOMAPT | |
| SCHEMBL15379639 | 0.66 | ACHE (0.67) | LMNAMAPK1HTTMPOMAPT | |
| SCHEMBL20730852 | 0.65 | CHRM2 (0.65) | NPSR1CNR1MITFLMNACNR2 | |
| SCHEMBL31324156 | 0.65 | KDM4E (0.81) | LMNAHTTMEN1KMT2AMAPT | |
| SCHEMBL11583277 | 0.64 | HTR2A (0.69) | NPSR1CNR1MITFLMNACNR2 | |
| SCHEMBL10045186 | 0.63 | CHRM2 (0.88) | LMNAMPOCHRM2ACHE | |
| Hydrochloric Acid SCHEMBL9501139 | 0.62 | SCN5A (0.53) | LMNAMEN1KMT2ASCN5AFOLH1 | |
| Hydrochloric Acid SCHEMBL31087727 | 0.62 | KDM4E (0.57) | MITFMPOMEN1KMT2AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146923-A1 | COMPOSITIONS AND METHODS FOR INHIBITION AND TARGETING OF P97 | CALIFORNIA INST OF TECHN (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230146923-A1 | COMPOSITIONS AND METHODS FOR INHIBITION AND TARGETING OF P97 | HSP90B1, CDC37, HDLBP | VPS4B 920/4885VCP 29/4885NPSR1 3859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.