Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21800033 | 0.82 | CHRM2 (0.46) | CHRM2L3MBTL1LMNACYP2D6 | |
| SCHEMBL20850656 | 0.81 | MAOA (0.64) | CHRM2L3MBTL1SCN8AMPOHDAC3 | |
| SCHEMBL10045186 | 0.81 | CHRM2 (0.88) | CHRM2L3MBTL1LMNASCN8AMPO | |
| SCHEMBL24850510 | 0.79 | L3MBTL1 (0.47) | CHRM2L3MBTL1SCN8AMAPK1NPSR1 | |
| SCHEMBL10045185 | 0.79 | CHRM2 (0.92) | CHRM2L3MBTL1LMNASCN8AMPO | |
| SCHEMBL14262442 | 0.77 | SCN8A (0.50) | CHRM2LMNASCN8AMITFCYP2D6 | |
| SCHEMBL25481133 | 0.77 | CHRM2 (0.73) | CHRM2LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL170986 | 0.77 | LMNA (0.64) | CHRM2L3MBTL1LMNAMITFCNR1 | |
| SCHEMBL8613857 | 0.77 | CHRM2 (0.67) | CHRM2L3MBTL1LMNASCN8AMPO | |
| SCHEMBL16522409 | 0.76 | MAOA (0.68) | CHRM2L3MBTL1SCN8AHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019032941-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-02-14 | — | — | WO | disclosed |