Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3142532 | 0.78 | CYP11B2 (0.68) | CYP11B2CYP11B1CYP19A1ALDH1A1MEN1 | |
| SCHEMBL1302 | 0.78 | ALDH1A1 (0.53) | CYP19A1ALDH1A1CYP2A6TSHRMAOB | |
| SCHEMBL2357484 | 0.74 | ALDH1A1 (0.50) | CYP19A1ALDH1A1CYP2A6TSHRMAOB | |
| SCHEMBL28995582 | 0.74 | ALDH1A1 (0.50) | CYP19A1ALDH1A1CYP2A6TSHRMAOB | |
| SCHEMBL27302597 | 0.74 | ALDH1A1 (0.50) | CYP19A1ALDH1A1CYP2A6TSHRMAOB | |
| SCHEMBL27685381 | 0.74 | ALDH1A1 (0.50) | CYP19A1ALDH1A1CYP2A6TSHRMAOB | |
| SCHEMBL28021948 | 0.74 | ALDH1A1 (0.50) | CYP19A1ALDH1A1CYP2A6TSHRMAOB | |
| SCHEMBL29124096 | 0.74 | ALDH1A1 (0.50) | CYP19A1ALDH1A1CYP2A6TSHRMAOB | |
| SCHEMBL22711559 | 0.74 | ALDH1A1 (0.50) | CYP19A1ALDH1A1CYP2A6TSHRMAOB | |
| SCHEMBL27706557 | 0.74 | MAOB (0.59) | CYP19A1ALDH1A1CYP2A6TSHRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123674-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-06 | — | — | WO | claimed |
| CN-112585137-A | Pesticidally active bicyclic heteroaromatic compounds | 先正达农作物保护股份公司 | 2021-03-30 | — | — | CN | disclosed |
| WO-2011123674-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-06 | — | — | WO | disclosed |