Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1302 | 0.96 | ALDH1A1 (0.53) | ALDH1A1MAOBTSHRCYP2A6NFE2L2 | |
| SCHEMBL28995582 | 0.92 | ALDH1A1 (0.50) | ALDH1A1MAOBTSHRCYP2A6NFE2L2 | |
| SCHEMBL29124096 | 0.92 | ALDH1A1 (0.50) | ALDH1A1MAOBTSHRCYP2A6NFE2L2 | |
| SCHEMBL22711559 | 0.92 | ALDH1A1 (0.50) | ALDH1A1MAOBTSHRCYP2A6NFE2L2 | |
| SCHEMBL291507 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MAOBTSHRCYP2A6NFE2L2 | |
| SCHEMBL29111027 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAOBTSHRCYP2A6NFE2L2 | |
| SCHEMBL439444 | 0.85 | G6PD (0.54) | MAOBTSHRCYP2A6NFE2L2LMNA | |
| SCHEMBL5946614 | 0.85 | ESR1 (0.54) | ALDH1A1MAOBCYP19A1MAOALMNA | |
| SCHEMBL7441695 | 0.85 | G6PD (0.54) | ALDH1A1MAOBTSHRCYP2A6NFE2L2 | |
| SCHEMBL5253400 | 0.85 | MAOA (0.71) | ALDH1A1MAOBTSHRCYP19A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994372-B2 | Parylene variants and methods of synthesis and use | SPECIALTY COATING SYSTEMS, INC. (US) | 2011-08-09 | — | — | US | disclosed |
| US-20090186998-A1 | PARYLENE VARIANTS AND METHODS OF SYNTHESIS AND USE | SPECIALTY COATING SYSTEMS, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| US-7462750-B2 | Parylene variants and methods of synthesis and use | SPECIALTY COATING SYSTEMS, INC. (US) | 2008-12-09 | — | — | US | disclosed |
| EP-1943200-A2 | PARYLENE VARIANTS AND METHODS OF SYNTHESIS AND USE | Specialty Coating Systems, Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007055822-A2 | PARYLENE VARIANTS AND METHODS OF SYNTHESIS AND USE | SPECIALTY COATING SYSTEMS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| US-20070099019-A1 | Parylene variants and methods of synthesis and use | SPECIALTY COATING SYSTEMS, INC. (US) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099019-A1 | Parylene variants and methods of synthesis and use | CDC73, PARN, PFAS | ALDH1A1 3048/4885MAOB 862/4885TSHR 2174/4885 |
| US-20090186998-A1 | PARYLENE VARIANTS AND METHODS OF SYNTHESIS AND USE | CDC73, PARN, PFAS | ALDH1A1 2365/4885MAOB 733/4885TSHR 2311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.