Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 12/20 | 0.46 |
| ▸ | PARP1 | P09874 | 11/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 10/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | GPR4 | P46093 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2244550 | 1.00 | TNKS (0.46) | TNKSPARP1PARP2MAPTHDAC3 | |
| SCHEMBL2247888 | 0.90 | MMP2 (0.47) | TNKSPARP1PARP2MAPTHDAC3 | |
| SCHEMBL2553025 | 0.90 | MMP2 (0.47) | TNKSPARP1PARP2MAPTHDAC3 | |
| SCHEMBL14637530 | 0.78 | MAPT (0.55) | TNKSPARP1PARP2MAPTHDAC3 | |
| SCHEMBL2246770 | 0.77 | TNKS (0.42) | TNKSPARP1PARP2MAPTHDAC3 | |
| SCHEMBL2550241 | 0.77 | TNKS (0.42) | TNKSPARP1PARP2MAPTHDAC3 | |
| SCHEMBL14637620 | 0.73 | TNKS (0.54) | TNKSPARP1PARP2MAPTHDAC3 | |
| SCHEMBL12026462 | 0.73 | HTR4 (0.54) | MAPTPOLBGRM5 | |
| SCHEMBL12049758 | 0.72 | GRM5 (0.54) | MAPTPOLBGRM5 | |
| SCHEMBL2547059 | 0.72 | POLB (0.47) | MAPTPOLBGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263628-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2011-10-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263628-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | HNMT, HCAR2, HPGD | TNKS 3298/4885PARP1 1144/4885PARP2 1017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.