Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | NOTCH1 | P46531 | 3/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21902866 | 0.86 | NR1H2 (0.48) | KDM1AUSP30NR1H2ABHD6ESR2 | |
| SCHEMBL16794188 | 0.86 | NR1H2 (0.48) | KDM1AUSP30NR1H2ABHD6ESR2 | |
| SCHEMBL13190426 | 0.78 | ABHD6 (0.51) | NR1H2ABHD6ESR2DPP8DPP9 | |
| SCHEMBL20533478 | 0.76 | KIF11 (0.40) | KDM1AKIF11ABHD6NAMPTDPP8 | |
| SCHEMBL20533479 | 0.76 | KIF11 (0.40) | KDM1AKIF11ABHD6NAMPTDPP8 | |
| SCHEMBL16794499 | 0.70 | NR1H2 (0.48) | KDM1AUSP30NR1H2ABHD6FNTA | |
| SCHEMBL20053977 | 0.68 | KDM1A (0.35) | KDM1AKIF11 | |
| SCHEMBL4718766 | 0.68 | USP30 (0.42) | USP30NR1H2FNTAFNTBESR2 | |
| SCHEMBL12279527 | 0.68 | USP30 (0.47) | USP30NR1H2KIF11ABHD6ESR2 | |
| SCHEMBL30970501 | 0.68 | USP30 (0.47) | USP30NR1H2KIF11ABHD6ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230147490-A1 | INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | BIOGEN MA INC. | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230147490-A1 | INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | ABL1, BTK, LYN | KDM1A 1524/4885USP30 2098/4885NR1H2 4173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.