Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19262730 | 0.89 | — | — | |
| SCHEMBL19520703 | 0.89 | ADAMTS5 (0.47) | ANPEPNPC1RAB9A | |
| SCHEMBL19534376 | 0.89 | ADAMTS5 (0.47) | ANPEPNPC1RAB9A | |
| SCHEMBL19520702 | 0.89 | ADAMTS5 (0.47) | ANPEPNPC1RAB9A | |
| SCHEMBL21082092 | 0.88 | ANPEP (0.40) | ANPEP | |
| SCHEMBL21046331 | 0.87 | — | — | |
| SCHEMBL15235778 | 0.87 | — | — | |
| SCHEMBL15227416 | 0.87 | — | — | |
| SCHEMBL255220 | 0.87 | NPC1 (0.41) | NPC1RAB9A | |
| SCHEMBL21046243 | 0.86 | ANPEP (0.38) | ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031298-A2 | ETHYNYLBENZENE DERIVATIVES | DUKE UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |