Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 7/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21046242 | 1.00 | ANPEP (0.38) | ANPEP | |
| SCHEMBL21046241 | 1.00 | ANPEP (0.38) | ANPEP | |
| SCHEMBL21082092 | 0.89 | ANPEP (0.40) | ANPEP | |
| SCHEMBL19534376 | 0.88 | ADAMTS5 (0.47) | ANPEP | |
| SCHEMBL19520702 | 0.88 | ADAMTS5 (0.47) | ANPEP | |
| SCHEMBL19520703 | 0.88 | ADAMTS5 (0.47) | ANPEP | |
| SCHEMBL254900 | 0.86 | ANPEP (0.39) | ANPEP | |
| SCHEMBL19520681 | 0.80 | NPC1 (0.50) | ANPEP | |
| SCHEMBL19520682 | 0.80 | NPC1 (0.50) | ANPEP | |
| SCHEMBL21046337 | 0.80 | NPC1 (0.50) | ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4286001-A2 | BENZOYLGLYCINE DERIVATIVES AND METHODS OF MAKING AND USING SAME | Duke University (US) | 2023-12-06 | — | — | EP | disclosed |
| US-20210206715-A1 | Benzoylglycine Derivatives and Methods of Making and Using Same | DUKE UNIVERSITY (US) | 2021-07-08 | — | — | US | disclosed |
| US-11034649-B2 | Benzoylglycine derivatives and methods of making and using same | DUKE UNIVERSITY (US) | 2021-06-15 | — | — | US | disclosed |
| US-10550074-B2 | Benzoylglycine derivatives and methods of making and using same | DUKE UNIVERSITY (US) | 2020-02-04 | — | — | US | disclosed |
| US-20190169114-A1 | Benzoylglycine Derivatives and Methods of Making and Using Same | DUKE UNIVERSITY | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206715-A1 | Benzoylglycine Derivatives and Methods of Making and Using Same | B3GAT3, GLO1, GLMN | ANPEP 1118/4885 |
| US-11034649-B2 | Benzoylglycine derivatives and methods of making and using same | B3GAT3, GLO1, GLMN | ANPEP 1118/4885 |
| US-20190169114-A1 | Benzoylglycine Derivatives and Methods of Making and Using Same | B3GAT3, GLO1, GLMN | ANPEP 1118/4885 |
| US-10550074-B2 | Benzoylglycine derivatives and methods of making and using same | B3GAT3, GLO1, GLMN | ANPEP 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.