Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25490264 | 0.83 | LIMK1 (0.40) | MAPTMEN1KMT2ANPSR1KDM4E | |
| SCHEMBL2534139 | 0.79 | LIMK1 (0.44) | MAPTMEN1KMT2ANPSR1KDM4E | |
| SCHEMBL19119483 | 0.76 | LIMK1 (0.57) | MAPTMEN1KMT2ANPSR1KDM4E | |
| SCHEMBL19325077 | 0.76 | MAPT (0.51) | MAPTMEN1KMT2ANPSR1KDM4E | |
| SCHEMBL16902632 | 0.74 | ALDH1A1 (0.47) | MAPTMEN1KMT2ANPSR1KDM4E | |
| SCHEMBL30646362 | 0.74 | ALDH1A1 (0.47) | MAPTMEN1KMT2ANPSR1KDM4E | |
| SCHEMBL16905650 | 0.74 | HRH4 (0.42) | MAPTMEN1KMT2ANPSR1KDM4E | |
| SCHEMBL2536243 | 0.73 | PIM1 (0.45) | MAPTMEN1KMT2ANPSR1KDM4E | |
| SCHEMBL13992526 | 0.73 | EGFR (0.42) | MAPTMEN1KMT2ANPSR1HSD17B10 | |
| SCHEMBL1512630 | 0.72 | GPR3 (0.40) | MAPTMEN1KMT2ANPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078812-A1 | BENZOFURO[3,2-D]PYRIMIDINO-2,4-DICARBONITRIL DERIVATIVES AND SIMILAR COMPOUNDS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2023-05-11 | — | — | WO | disclosed |