Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.72 |
| ▸ | DRD2 | P14416 | 4/20 | 0.68 |
| ▸ | HTR2A | P28223 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7982019 | 0.98 | SIGMAR1 (0.70) | SIGMAR1DRD2HTR2AKMT2AMEN1 | |
| SCHEMBL2550320 | 0.98 | SIGMAR1 (0.70) | SIGMAR1DRD2HTR2AKMT2AMEN1 | |
| SCHEMBL7972984 | 0.95 | DRD2 (0.69) | SIGMAR1DRD2HTR2AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7983779 | 0.94 | DRD2 (0.68) | SIGMAR1DRD2HTR2AKMT2AMEN1 | |
| SCHEMBL10153569 | 0.89 | KMT2A (0.69) | SIGMAR1DRD2HTR2AKMT2AMEN1 | |
| SCHEMBL18770805 | 0.89 | DRD2 (0.82) | SIGMAR1DRD2HTR2AKMT2AMEN1 | |
| SCHEMBL16980657 | 0.85 | SIGMAR1 (0.72) | SIGMAR1DRD2HTR2AKMT2AMEN1 | |
| SCHEMBL25237094 | 0.84 | SIGMAR1 (1.00) | SIGMAR1DRD2HTR2AKMT2AMEN1 | |
| SCHEMBL10723980 | 0.84 | SIGMAR1 (0.70) | SIGMAR1DRD2HTR2AKMT2AMEN1 | |
| SCHEMBL10724043 | 0.84 | SIGMAR1 (0.70) | SIGMAR1DRD2HTR2AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121055-A1 | PYRIDINYL DERIVATIVES COMPRISING A CYANOGUANIDINE OR SQUARIC ACID MOIETY | TOPOTARGET A/S (DK) | 2011-10-06 | — | — | WO | disclosed |
| WO-2011121055-A1 | PYRIDINYL DERIVATIVES COMPRISING A CYANOGUANIDINE OR SQUARIC ACID MOIETY | TOPOTARGET A/S (DK) | 2011-10-06 | — | — | WO | disclosed |
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| CN-1223659-A | Fused imidazopyridine derivatives as antihyperlipidemic agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-07-21 | — | — | CN | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |