Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2544118 | 0.92 | GRM8 (0.33) | GRM8GRM4SLC6A9UTS2R | |
| SCHEMBL1596367 | 0.85 | AKR1C3 (0.33) | GRM8GRM4SLC6A9 | |
| SCHEMBL1742907 | 0.80 | PDE2A (0.33) | GRM8GRM4UTS2R | |
| SCHEMBL2547956 | 0.80 | PDE2A (0.33) | GRM8GRM4UTS2R | |
| SCHEMBL2551183 | 0.80 | FFAR1 (0.33) | — | |
| SCHEMBL2541349 | 0.78 | TEAD1 (0.31) | — | |
| SCHEMBL2548062 | 0.77 | CES2 (0.32) | SLC6A9 | |
| SCHEMBL12241695 | 0.76 | PPARG (0.37) | UTS2R | |
| SCHEMBL1742760 | 0.73 | TEAD1 (0.35) | SLC6A9 | |
| SCHEMBL1594372 | 0.73 | FFAR1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263647-A1 | FLUOROISOQUINOLINE SUBSTITUTED THIAZOLE COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263647-A1 | FLUOROISOQUINOLINE SUBSTITUTED THIAZOLE COMPOUNDS AND METHODS OF USE | TFEB, PCK2, JAK2 | GRM8 3910/4885GRM4 2696/4885SLC6A9 4142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.