SCHEMBL25494615

SCHEMBL25494615

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nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.62
▸ THRB P10828 1/20 0.62
▸ MAPK1 P28482 2/20 0.60
▸ CD69 Q07108 1/20 0.53
▸ SMN1; SMN2 Q16637 1/20 0.52
▸ POLB P06746 1/20 0.48
▸ MEN1 O00255 1/20 0.47
▸ KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25751787 1.00 ALDH1A1 (0.62) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL24239542 1.00 ALDH1A1 (0.62) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL12227671 1.00 ALDH1A1 (0.62) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL22021019 1.00 ALDH1A1 (0.62) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL25446681 1.00 ALDH1A1 (0.62) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL24004407 1.00 ALDH1A1 (0.62) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL24004417 1.00 ALDH1A1 (0.62) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL24239885 1.00 ALDH1A1 (0.62) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL23692740 1.00 ALDH1A1 (0.62) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL20713635 1.00 ALDH1A1 (0.62) ALDH1A1THRBMAPK1CD69SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-09-07 — — US disclosed
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-09-07 — — US disclosed
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-07-20 — — US disclosed
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-07-20 — — US disclosed
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 — — US disclosed
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates M6PR, ASGR1, IGF2R ALDH1A1 3655/4885THRB 1793/4885MAPK1 2043/4885
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION HAVCR2, FCGR3B, FCGR2A ALDH1A1 4520/4885THRB 1640/4885MAPK1 3302/4885
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION HAVCR2, ASGR1, FCGR3B ALDH1A1 4368/4885THRB 1271/4885MAPK1 3065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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