Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL880931 | 0.90 | NPC1 (0.49) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6904762 | 0.89 | NPC1 (0.44) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29365942 | 0.88 | NPC1 (0.64) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL208288 | 0.88 | NPC1 (0.64) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| Bumetrizole SCHEMBL8054070 | 0.88 | NPC1 (0.53) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL22606047 | 0.88 | NPC1 (0.50) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| Bumetrizole SCHEMBL8056551 | 0.88 | NPC1 (0.53) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL22589019 | 0.88 | NPC1 (0.50) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| Bumetrizole SCHEMBL23734 | 0.88 | NPC1 (0.53) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| Bumetrizole SCHEMBL8603228 | 0.88 | NPC1 (0.53) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988518-B2 | Chlorine-resistant crosslinkable polyolefin compositions and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2018-06-05 | — | — | US | claimed |
| US-20150132518-A1 | CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. | 2015-05-14 | — | — | US | claimed |
| US-8962718-B2 | Chlorine-resistant crosslinkable polyolefin compositions and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2015-02-24 | — | — | US | claimed |
| EP-3712138-A1 | BENZOTRIAZOLE COMPOUND | Miyoshi Oil & Fat Co., Ltd. (JP) | 2020-09-23 | — | — | EP | disclosed |
| US-9988518-B2 | Chlorine-resistant crosslinkable polyolefin compositions and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2018-06-05 | — | — | US | disclosed |
| EP-2563827-B1 | CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2017-06-21 | — | — | EP | disclosed |
| US-20150132518-A1 | CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. | 2015-05-14 | — | — | US | disclosed |
| US-8962718-B2 | Chlorine-resistant crosslinkable polyolefin compositions and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2015-02-24 | — | — | US | disclosed |
| EP-2563827-A1 | CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM | Momentive Performance Materials Inc. (US) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011139635-A1 | CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-11-10 | — | — | WO | disclosed |
| US-20110259464-A1 | CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-10-27 | — | — | US | disclosed |